Bobo Feng et al. The main stabilizer of the DNA double helix is not the base-pair hydrogen bonds but coin-pile stacking of base pairs, whose hydrophobic cohesion, requiring abundant water, indirectly makes the DNA interior dry so that hydrogen bonds can exert full recognition power. We report that certain semihydrophobic agents depress the stacking energy … Continue reading Hydrophobic Catalysis and a Potential Biological Role of DNA Unstacking Induced by Environmental Effects