Sudden Deaths of 80 Young Canadian Doctors Since Rollout of COVID-19 Vaccines

William Makis A Letter to the Canadian medical Association (CMA) On September 3, 2022, I wrote you a letter regarding the sudden and unexpected deaths of 32 young Canadian doctors since the rollout of COVID‐19 vaccines, and I raised concerns about COVID‐19 vaccines and vaccine mandates contributing to these sudden deaths. … There has been […]

Beneficial Properties of Bromelain

sliced pineapple on white ceramic plate

Pawel Hikisz and Joanna Bernaskinska-Slomczewska Beneficial Properties of Bromelain Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high availability, and relative simplicity of acquisition, it is the object of inexhaustible interest of scientists. This review summarizes scientific […]

Possible Beneficial Effects of Fresh Pomegranate Juice in SARS-CoV-2 Infection Conditions

clear drinking glass with red liquid on brown wooden round table

Saleem Ali Banihani Rather than the prophylactic vaccination, any effective synthetic, natural, or nutritional therapy or regimen that may cure or remedy, albeit partially, the complications of SARS-CoV-2 should be highly acknowledged. Here, we reviewed and discussed possible beneficial biological effects of pomegranate juice in such diseased condition of viral infection based on the current […]

Using Lipid Nanoparticles to Efficiently Deliver CRISPR/Cas9 for Genome Editing

S. C. Alexander et al. Transthyretin amyloidosis (ATTR) is a progressive disease caused by accumulation of amyloid deposits of misfolded transthyretin (TTR) protein in multiple tissues including the heart, nerves and gastrointestinal tract. Reduction of TTR monomer via stabilization of circulating tetramer and silencing of TTR gene expression in hepatocytes of ATTR patients have emerged […]

At NY Genome Center, Legal Expert Presents Ethical Dilemmas in Gene Editing

fapnewstoday.com Developing gene therapies for rare diseases is one thing. Creating gene-edited “designer babies” is quite another. German legal expert Timo Minssen outlined the potentially explosive ethical landmines surrounding such issues during a recent talk at the New York Genome Center. … Minssen said the rapidly growing global market for CRISPR/Cas9 technology could reach $10 […]

Gene-editing Therapy NTLA-2001 Given Orphan Drug Status by FDA

fapnewstoday.com The U.S. Food and Drug Administration (FDA) has given orphan drug designation to NTLA- 2001, an investigational gene-editing therapy for familial amyloid polyneuropathy (FAP) and other forms of transthyretin (ATTR) amyloidosis. … The aim of NTLA-2001 is to disrupt the TTR gene, thus decreasing transthyretin production and preventing the buildup of these harmful protein […]

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

Julian D. Gillmore et al. Transthyretin amyloidosis, also called ATTR amyloidosis, is a life-threatening disease characterized by progressive accumulation of misfolded transthyretin (TTR) protein in tissues, predominantly the nerves and heart. NTLA-2001 is an in vivo gene-editing therapeutic agent that is designed to treat ATTR amyloidosis by reducing the concentration of TTR in serum. It […]