Fundamental Flaws in Pfizer’s COVID-19 Biologics License Application Submission, and the Implications to the Safety and Effectiveness of These Novel Gene Therapy Vaccines
Philip R. Oldfield and Maria L. Gutschi The mRNA COVID-19 vaccines are using gene therapy technology in which the active product, the encoded spike protein, is not actually part of the formulation. Health Canada has used an inappropriate guidance document for the regulatory review, contrary to Good Scientific Practice, effectively compromising the safety of Canadians. […]
A New Pre-print Answers Some Questions About Age-related Immunopathologies Associated with empty LNPs
Jessica Rose A new preprint was uploaded on November 7, 2022 entitled: “Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals” by a ‘non-conflicted group of researchers’ from… Acuitas? Wait, what? … Acuitas is the Canadian Biotech company that makes the proprietary Pfizer/BioNTech LNPs. … the paper reveals […]
If We Don’t Know What’s in Covid Vaccines, How Can We Know What They’re Doing?
Rhoda Wilson Some researchers are finding graphene while others are not. There are many reports of degraded, low-purity mRNA while other researchers find there is none. Because vaccine manufacturers’ contracts prohibit independent analysis of their “vaccines” it’s difficult to legally obtain enough samples, from a broad spectrum of batches and locations, to establish what is […]
Yes, mRNA Vaccines Are Different. Here’s Why.
Ah Kahn Syed How are mRNA vaccines different from traditional vaccines? Here’s the list. (1) they contain mRNA, not protein or inactivated virus. (2) they contain LNPs (lipid nanoparticles) which are transfectants and transport those RNAs into the cells of the recipient in order to do this. (3) they distribute to and accumulate in the the ovaries and express […]
Skin Testing with Pfizer SARS-Cov-2 Vaccine and PEG 2000
João Vieira et al. The Pfizer-BioNTech SARS-CoV-2 vaccine is an mRNA vaccine that uses a lipid-based nanoparticle carrier system, stabilized by polyethylene glycol (PEG) 2000. Although evidence on the pathogenesis of severe immediate reactions to the SARS-CoV-2 vaccine is lacking, the PEG molecule has been proposed as a possible culprit for these reactions due to […]
Anaphylactic Reactions to mRNA COVID-19 Vaccines: A Call for Further Study
Sophia Hatziantoniou et al. The modified mRNA molecule is encased in LNPs, consisting of ionizable, auxiliary and pegylated lipids, as well as cholesterol, which is thought to contribute to the fluidity of the nanoparticle, thus increasing its ability to fuse with the plasma membranes of host cells to deliver the mRNA cargo. … After implementation […]
mRNA Vaccines to Prevent COVID-19 Disease and Reported Allergic Reactions: Current Evidence and Suggested Approach
Aleena Banerji et al. The U.S. Food and Drug Administration (FDA) has recently issued an Emergency Use Authorization (EUA) for 2 highly effective coronavirus disease 2019 (COVID-19) vaccines from Pfizer-BioNTech and Moderna. This has brought hope to millions of Americans in the midst of an ongoing global pandemic. The FDA EUA guidance for both vaccines […]
Polyethylene Glycol (PEG) is a Cause of Anaphylaxis to the Pfizer/BioNTech mRNA COVID-19 Vaccine
Priya Sellaturay et al. Allergy to PEG is rare,5,6 but reactions can be severe or even fatal.7 PEG is an excipient of many drugs, but hypersensitivity de- pends on its molecular weight (MW). … Although the Pfizer/BioNTech vaccine contains a number of excipients, PEG 2000 is the only one reported to cause anaphylaxis. All mRNA […]
