Katharina Wylon, Sabine Dölle, Margitta Worm
Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food.
Potential life-threatening hypersensitivity reactions to hidden molecules like macrogol may be under- diagnosed. Cases of immediate-type PEG hypersensitivity were reported with increasing frequency. The awareness regarding the allergenic potential of PEG should be raised and a proper product labelling is crucial to prevent PEG mediated hypersensitivity.