Chitin and Its Effects on Inflammatory and Immune Responses
Daniel Elieh Ali Komi, Lokesh Sharma and Charles S. Dela Cruz Chitin, a potential allergy-promoting pathogen-associated molecular pattern (PAMP), is a linear polymer composed of N-acetylglucosamine residues which are linked by β-(1,4)-glycosidic bonds. Mammalians are potential hosts for chitin-containing protozoa, fungi, arthropods, and nematodes; however, mammalians themselves do not synthetize chitin and thus it is […]
Cumulative Inactivated Vaccine Exposure and Allergy Development Among Children: A Birth Cohort from Japan
Kiwako Yamamoto-Hanada et al. Adjuvants used in inactivated vaccines often upregulate type 2 immunity, which is dominant in allergic diseases. We hypothesised that cumulative adjuvant exposure in infancy may influence the development of allergies later in life by changing the balance of type 1/type 2 immunity. We examined the relationship between immunisation with different vaccine […]
