Pre-exposure to mRNA-LNP Inhibits Adaptive Immune Responses and Alters Innate Immune Fitness in an Inheritable Fashion
Zhen Qin et al. Hundreds of millions of SARS-CoV-2 mRNA-LNP vaccine doses have already been administered to humans. However, we lack a comprehensive understanding of the immune effects of this platform. The mRNA-LNP-based SARS-CoV-2 vaccine is highly inflammatory, and its synthetic ionizable lipid component responsible for the induction of inflammation has a long in vivo […]
Pre-exposure to mRNA-LNP Inhibits Adaptive Immune Responses and Alters Innate Immune Fitness in an Inheritable Fashion
Zhen Qin, Aurélie Bouteau, Christoper Herbst, Botond Z. Igyártó Hundreds of millions of SARS-CoV-2 mRNA-LNP vaccine doses have already been administered to humans. However, we lack a comprehensive understanding of the immune effects of this platform. The mRNA-LNP-based SARS-CoV-2 vaccine is highly inflammatory, and its synthetic ionizable lipid component responsible for the induction of inflammation […]
