Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

shallow focus photography of green leaves

Richard B. van Breemen et al. Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthostericligands with micromolar affinity for the spike protein. In follow-up virus neutralization assays, cannabigerolic acid and cannabidiolic acid prevented infection of human epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike protein and prevented entry […]