Dietary Copper and Human Health: Current Evidence and Unresolved Issues
Muriel Bost et al. Although copper (Cu) is recognized as an essential trace element, uncertainties remain regarding Cu reference values for humans, as illustrated by discrepancies between recommendations issued by different national authorities. This review examines human studies published since 1990 on relationships between Cu intake, Cu balance, biomarkers of Cu status, and health. It […]
Fruit and Vegetable Peels: Paving the Way Towards the Development of New Generation Therapeutics
Hamendra S. Parmar et al. Interestingly, the last few years have seen an increase in the number of available reports on fruits and vegetable peels, and particularly on their biological activity, their content of different bioactive compounds, their chemical characterization, understanding of their structure-activity relationships, isolation and purification of commercially important chemicals without using high […]
Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases
Hongjie Chen et al. Cardiovascular disease (CVD) is the leading cause of death in the world and our approach to the control and management of CVD mortality is limited. Nattokinase (NK), the most active ingredient of natto, possesses a variety of favourable cardiovascular effects and the consumption of Natto has been linked to a reduction […]
Potential Cardiotoxic Effects of Remdesivir on Cardiovascular System: A Literature Review
Maryam Nabati and Homa Parasee Corona disease 2019 (COVID-19) pandemic continues to spread around the world with no efficacious treatment. Intravenous remdesivir is the only authorized drug for treatment of COVID-19 disease under an Emergency Use Authorization. Remdesivir is a 1′-cyano-substituted adenosine nucleotide prodrug which inhibits viral RNA synthesis. This metabolite is an adenosine analog […]
Cardiovascular Drug Interactions with Nirmatrelvir/Ritonavir [Paxlovid] in Patients with COVID-19
Sonu Abraham et al. Nirmatrelvir-ritonavir (NMVr) is used to treat symptomatic, nonhospitalized patients with coronavirus disease-2019 (COVID-19) who are at high risk of progression to severe disease. Patients with cardiovascular risk factors and cardiovascular disease are at a high risk of developing adverse events from COVID-19 and as a result have a higher likelihood of […]
Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents
Suyanee Mansanguan et al. This study focuses on cardiovascular manifestation, particularly myocarditis and pericarditis events, after BNT162b2 mRNA COVID‐19 vaccine injection in Thai adolescents … We enrolled 314 participants; of these, 13 participants were lost to follow‐up, leaving 301 participants for analysis. The most common cardiovascular signs and symptoms were tachycardia (7.64%), shortness of breath […]
Increased Emergency Cardiovascular Events Among Under-40 Population in Israel During Vaccine Rollout and Third COVID-19 Wave
Christopher L.F. Sun, Eli Jaffe, Retsef Levi Cardiovascular adverse conditions are caused by coronavirus disease 2019 (COVID-19) infections and reported as side-effects of the COVID-19 vaccines. Enriching current vaccine safety surveillance systems with additional data sources may improve the understanding of COVID-19 vaccine safety. Using a unique dataset from Israel National Emergency Medical Services (EMS) […]
