Dietary Copper and Human Health: Current Evidence and Unresolved Issues

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Muriel Bost et al. Although copper (Cu) is recognized as an essential trace element, uncertainties remain regarding Cu reference values for humans, as illustrated by discrepancies between recommendations issued by different national authorities. This review examines human studies published since 1990 on relationships between Cu intake, Cu balance, biomarkers of Cu status, and health. It […]

Fruit and Vegetable Peels: Paving the Way Towards the Development of New Generation Therapeutics

orange peels

Hamendra S. Parmar et al. Interestingly, the last few years have seen an increase in the number of available reports on fruits and vegetable peels, and particularly on their biological activity, their content of different bioactive compounds, their chemical characterization, understanding of their structure-activity relationships, isolation and purification of commercially important chemicals without using high […]

Potential Cardiotoxic Effects of Remdesivir on Cardiovascular System: A Literature Review

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Maryam Nabati and Homa Parasee Corona disease 2019 (COVID-19) pandemic continues to spread around the world with no efficacious treatment. Intravenous remdesivir is the only authorized drug for treatment of COVID-19 disease under an Emergency Use Authorization. Remdesivir is a 1′-cyano-substituted adenosine nucleotide prodrug which inhibits viral RNA synthesis. This metabolite is an adenosine analog […]

Cardiovascular Manifestation of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents

Suyanee Mansanguan et al. This study focuses on cardiovascular manifestation, particularly myocarditis and pericarditis events, after BNT162b2 mRNA COVID‐19 vaccine injection in Thai adolescents … We enrolled 314 participants; of these, 13 participants were lost to follow‐up, leaving 301 participants for analysis. The most common cardiovascular signs and symptoms were tachycardia (7.64%), shortness of breath […]

Increased Emergency Cardiovascular Events Among Under-40 Population in Israel During Vaccine Rollout and Third COVID-19 Wave

Christopher L.F. Sun, Eli Jaffe, Retsef Levi Cardiovascular adverse conditions are caused by coronavirus disease 2019 (COVID-19) infections and reported as side-effects of the COVID-19 vaccines. Enriching current vaccine safety surveillance systems with additional data sources may improve the understanding of COVID-19 vaccine safety. Using a unique dataset from Israel National Emergency Medical Services (EMS) […]