Tag: ECM stiffness

Extracellular Matrix and Its Therapeutic Potential for Cancer Treatment

Jiacheng Huang et al. The extracellular matrix (ECM) is one of the major components of tumors that plays multiple crucial roles, including mechanical support, modulation of the microenvironment, and a source of signaling molecules. The quantity and cross-linking status of ECM components are major factors determining tissue stiffness. During tumorigenesis, the interplay between cancer cells […]