Influenza Vaccination: Policy Versus Evidence
Tom Jefferson Each year enormous effort goes into producing influenza vaccines for that specific year and delivering them to appropriate sections of the population. Is this effort justified? Public policy worldwide recommends the use of inactivated influenza vaccines to prevent seasonal outbreaks. Because viral circulation and antigenic match vary each year and non-randomised studies predominate, […]
Vaccines for Preventing Influenza in healthy Adults
Vittorio Demicheli et al. We found 52 clinical trials of over 80,000 adults. We were unable to determine the impact of bias on about 70% of the included studies due to insufficient reporting of details. Around 15% of the included studies were well designed and conducted. We focused on reporting of results from 25 studies […]