Using Lipid Nanoparticles to Efficiently Deliver CRISPR/Cas9 for Genome Editing

S. C. Alexander et al. Transthyretin amyloidosis (ATTR) is a progressive disease caused by accumulation of amyloid deposits of misfolded transthyretin (TTR) protein in multiple tissues including the heart, nerves and gastrointestinal tract. Reduction of TTR monomer via stabilization of circulating tetramer and silencing of TTR gene expression in hepatocytes of ATTR patients have emerged […]

Gene-editing Therapy NTLA-2001 Given Orphan Drug Status by FDA

fapnewstoday.com The U.S. Food and Drug Administration (FDA) has given orphan drug designation to NTLA- 2001, an investigational gene-editing therapy for familial amyloid polyneuropathy (FAP) and other forms of transthyretin (ATTR) amyloidosis. … The aim of NTLA-2001 is to disrupt the TTR gene, thus decreasing transthyretin production and preventing the buildup of these harmful protein […]

mRNA Vaccines Against COVID-19 and Their Effects on the Central Nervous System

Michael Palmer, Sucharit Bhakdi This document was written to answer three questions posed to us by a lawyer who is challenging COVID-19 vaccine approvals and mandates in his home country. The answers may be of interest to the readers of this website as well. 1. What evidence is currently available to show that mRNA vaccine […]

How Masking Contributes to Long Covid

Carla Peeters A lingering disorder that can last for months or years is affecting an increasing proportion of the workforce. The symptoms that contribute to Long Covid could be a result of pandemic measures and masking in particular. Increased exposure to microplastics, nanoparticles, chemicals in masks and nasopharyngeal tests parallel many of the symptoms that […]

Working Group for COVID Vaccine Analysis: Summary of Preliminary Findings

German Working Group for COVID Vaccine Analysis Report date: July 6, 2022 SUMMARY OF PRELIMINARY FINDINGS The German Working Group for COVID Vaccine Analysis has made its initial findings publicly available in a wide-ranging report: 1. Toxic substances were found in all of the samples of COVID-19 vaccines – without exception.2. The blood samples of […]

New Quality-control Investigations on Vaccines: Micro- and Nanocontamination

three people inside factory wearing masks and coats

Antonietta M. Gatti, Stefano Montanari Vaccines are being under investigation for the possible side e ects they can cause. In order to supply new information, an electron-microscopy investigation method was applied to the study of vaccines, aimed at verifying the presence of solid contaminants by means of an Environmental Scanning Electron Microscope equipped with an […]