Fatty Acids Derived from the Probiotic Lacticaseibacillus rhamnosus HA-114 Suppress Age-dependent Neurodegeneration
Audrey Labarre et al. The human microbiota is believed to influence health. Microbiome dysbiosis may be linked to neurological conditions like Alzheimer’s disease, amyotrophic lateral sclerosis, and Huntington’s disease. We report the ability of a probiotic bacterial strain in halting neurode- generation phenotypes. We show that Lacticaseibacillus rhamnosus HA-114 is neuroprotective in C. elegans models of amyotrophic lateral sclerosis […]
Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer’s Disease, Parkinson’s Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome
Takumi Satoh et al. Rosemary (Rosmarinus officinalis [family Lamiaceae]), an herb of economic and gustatory repute, is employed in traditional medicines in many countries. Rosemary contains carnosic acid (CA) and carnosol (CS), abietane-type phenolic diterpenes, which account for most of its biological and pharmacological actions, although claims have also been made for contributions of another […]
Glyphosate Weed Killer Crosses Blood-Brain Barrier, Linked to Alzheimer’s and Other Neurodegenerative Diseases
Beyond Pesticides An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFα and the accumulation of […]
Diminished Brain Resilience Syndrome: A Modern Day Neurological Pathology of Increased Susceptibility to Mild Brain Trauma, Concussion, and Downstream Neurodegeneration
Wendy A. Morley and Stephanie Seneff The number of sports-related concussions has been steadily rising in recent years. Diminished brain resilience syndrome is a term coined by the lead author to describe a particular physiological state of nutrient functional deficiency and disrupted homeostatic mechanisms leading to increased susceptibility to previously considered innocuous concussion. We discuss […]
Redox Biology in Neurological Function, Dysfunction and Aging
Rodrigo Franco and Marcelo R. Vargas Reduction oxidation (redox) reactions are central to life and when altered, they can promote disease progression. In the brain, redox homeostasis is recognized to be involved in all aspects of central nervous system (CNS) development, function, aging, and disease. Recent studies have uncovered the diverse nature by which redox […]
Detailed Investigation of Spike Protein Action Suggests Mechanisms for Adverse Effect Generation
Guy Hatchard SOME of the research work concerning Covid and Covid vaccination is centred around understanding why the spike protein is toxic and exactly how it affects elements of physiological systems. Some of the published papers involve complex investigation of physiological mechanisms. One published on June 14, 2022 in Cells journal examines lipid toxicity. Another published on May […]
