SARS-CoV-2 Spike Ectodomain Targets α7 Nicotinic Acetycholine Receptors

corona, coronavirus, virus

Brittany C. V. O’Brien et al. Virus entry into animal cells is initiated by attachment to target macromolecules located on host cells. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) trimeric spike glycoprotein targets host angiotensin converting enzyme 2 to gain cellular access. The SARS-CoV-2 glycoprotein contains a neurotoxin-like region that has sequence similarities to […]