Tiffany Parotto, James A. Thorp, Brian Hooker, Paul J. Mills, Jill Newman, Leonard Murphy, Warren Geick, Dan McDyer, Raphael B. Stricker, Sue Peters, Maureen McDonnell, Heather Ray, Christiane Northrup

In the survey, 292 women (4.83 % of the sample) reported having experienced DCS. The mean age of these predominantly non-Hispanic white women was 36.1 ± 0.5 (SEM) years. Eleven percent were taking hormonal contraceptives, 94.3% considered themselves healthy and 96.2% reported that menstrual irregularities started in 2021. According to Google metadata, search terms for “decidual cast shedding” substantially increased during the months of April, May, and June 2021. These peaks in searches represented a 2000% increase over the rst quarter of 2021.

Conclusions: There was a significant increase in self-reported DCS in the latter part of 2021 compared to all pre-pandemic cases. More research is urgently needed to investigate the factors contributing to DCS in 2021 and whether this trend is continuing.