How Vaccines Drive Covid Variants

Amanuensis

Variants have been one of the hallmarks of this pandemic, with ever more infectious forms of the virus apparently mutating themselves into existence at regular intervals.

… At the point that it was clear the vaccines weren’t sterilising, the theory behind what might be the ‘correct’ level of vaccination changes completely. With non-sterilising vaccines, ‘herd immunity’ becomes impossible and this goal should have been dropped immediately. But worse than that, the fact that the vaccines weren’t sterilising meant there was a large selective pressure for evolution and a sufficiently high viral ‘population’ in vaccinated individuals, and so this also meant that the virus could more effectively evolve vaccine escape.

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