Pharma Eyes Big Profits in Nasal Vaccines – Should We Really Spray Nanoparticles So Close to the Brain?

The Defender Staff

Vaccine manufacturers set their sights on nasal vaccines at least two decades ago, but so far product development has remained sluggish as scientists acknowledge that only a “thin partition” separates the nasal cavity from the brain.

… Would nasal sprays be more benign than their injectable counterparts? Experience thus far urges caution.

As an otherwise enthusiastic author wrote in 2020, in the journal Mucosal Vaccines, there is little doubt the “inflammatory immune responses” generated by the nose’s encounter with the vaccine antigen “would result in sustained pathologic inflammation.”

Another warning sign comes from testing of mucosal adjuvants (substances added to boost the immune response) in nasal vaccines.

… And the rise of nanoparticulate delivery systems with “yet to be established” safety profiles introduces a range of new questions about toxicity.

One area of concern is the proposed use of the “stealth polymer” polyethylene glycol (PEG) in nasal vaccines.

… PEG-related side effects reported in the literature include hypersensitivity reactions, “unexpected changes in pharmacokinetic behavior” (referring to the processes of “absorption, distribution, metabolism, and excretion”), “toxic side products” and “possible accumulation in the body.”

Latest articles

Anthony Jay Plastic has become part of modernity’s make-up (literally). Scientific discoveries...
Joseph Mercola An eight-month investigation revealed shocking aws in Merck’s clinical trial...
Suzanne Burdick The authors of a peer-reviewed study showing microplastics passed pregnant...
Kaayla Daniel The notion that the body can create proline and glycine...

Thank you!

Thank you for your membership application. As soon as your payment has been received your membership will be activated and you will be informed via email.

Thank you.

Thank you!

The form has been submitted successfully!