Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

Richard B. van Breemen et al.

Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthosteric
ligands with micromolar affinity for the spike protein. In follow-up virus neutralization assays, cannabigerolic acid and cannabidiolic acid prevented infection of human epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike protein and prevented entry of live SARS-CoV-2 into cells. Importantly, cannabigerolic acid and cannabidiolic acid were equally effective against the SARS CoV-2 alpha variant B.1.1.7 and the beta variant B.1.351. Orally bioavailable and with a long history of safe human use, these cannabinoids, isolated or in hemp extracts, have the potential to prevent as well as treat infection by SARS-CoV-2.

Latest articles

The Goddard Report A podcast with Dr. Stephen Malthouse on “Making Doctors...
www.OpenSourceTruth.com All previous outbreaks, epidemics and pandemics end when Community Immunity, NOT...
Amanuensis Variants have been one of the hallmarks of this pandemic, with...
Samuel Reinfeld et al. The COVID-19 pandemic continues to have a deleterious...

Thank you!

Thank you for your membership application. As soon as your payment has been received your membership will be activated and you will be informed via email.

Thank you.

Thank you!

The form has been submitted successfully!