Duration of Immune Protection of SARS-CoV-2 Natural Infection Against Infection in Qatar

Hiam Chemaitelly et al.

The future of the SARS-CoV-2 pandemic hinges on virus evolution and duration of immune protection of natural infection against reinfection. We investigated duration of protection afforded by natural infection, the effect of viral immune evasion on duration of protection, and protection against severe reinfection, in Qatar, between February 28, 2020 and June 5, 2022.

… We sought to answer three questions of relevance to the future of this pandemic: 1) When infected with a pre-Omicron variant, how long does protection persist against reinfection with pre-Omicron variants? 2) When infected with a pre-Omicron variant, how long does protection persist against reinfection with an Omicron subvariant? 3) When infected with any variant, how long does protection persist against severe, critical, or fatal COVID-19?

… These analyses were implemented using Qatar’s total population with large sample sizes, thus minimizing the likelihood of bias.

In conclusion, protection of natural infection against reinfection wanes and may diminish within a few years. Omicron immune evasion accelerates this waning. Meanwhile, protection against severe reinfection is very strong with no evidence for waning, regardless of variant, for over 14 months after the primary infection.

Latest articles

Carolyn Beans How “forever chemicals” might impair the immune system Stain-resistant carpets...
Harold E. Buttram, Susan Kreider and Alan R. Yurko The writers of...
Carla Peeters A lingering disorder that can last for months or years...
el gato malo … the CDC just dramatically changed their claims about...

Your donation helps us
stand up for health freedom!

Canada Health Alliance is volunteer run and 100% supported by the generous donations of those who share our concerns and value our work.

Stay up to date

Sign up to our newsletter to get the latest health-related news and events delivered straight to your inbox.

Become a CHA member

Become an active value-added member and trusted provider of medical and healthcare information and education by joining the CHA Membership Program.

Your donation helps us stand up for healthcare choice!

Canada Health Alliance is volunteer run and 100% supported by the generous donations of those who share our concerns and value our work.

Thank you!

The form has been submitted successfully!