Christina Ulm and Gabriele Weiß
“The concept of a cell is, strictly speaking, only a morphological abstraction. Seen from a biological point of view, a cell cannot be considered by itself without taking its environment into account.”
With these words Alfred Pischinger (MD) was the first scientist to describe the importance of the extracellular matrix (ECM) and to state that almost every disease starts within the ECM. To his opinion not only the regulations within cells (histological segmentation) play major role in regulation of body function, but the surrounding milieu.