Long-term Persistence of the SARS-CoV-2 Spike Protein: Evidence and Implications

Michael Palmer and Sucharit Bhakdi

This paper discusses the recent study by Bansal et al. [1] on the detection of spike protein in persons vaccinated with the Pfizer mRNA vaccine. The most significant finding is that spike protein is found on exosomes, that is, cell-derived vesicles, for at least four months after the second injection. This surprisingly long persistence raises the prospect of sustained inflammation within and damage to organs which express the spike protein.

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