Joel Smalley

The homologous recombination DNA repair pathway is one of the mechanisms that the body uses to stop your cells turning cancerous in response to environmental stress.

One of the most important components of this pathway is Tumor Protein P53 (p53), the “guardian of the genome”. It protects our cells from cellular damage. Under cellular stress, p53 jumps into action, regulating gene expression to control DNA repair, cell division and cell death. It is the most commonly mutated gene in cancer.