Vitamin D Deficiency in Association with Endothelial Dysfunction: Implications for Patients with COVID-19

Jun Zhang, Peter A. McCullough, Kristen M. Tecson

There is emerging evidence to suggest that vitamin D deficiency is associated with adverse outcomes in COVID-19 patients. Conversely, vitamin D supplementation protects against an initial alveolar diffuse damage of COVID-19 becoming progressively worse. The mechanisms by which vitamin D deficiency exacerbates COVID-19 pneumonia remain poorly understood. In this review we describe the rationale of the putative role of endothelial dysfunction in this event.

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